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CUMYL-4CN-BINACA (also known as SGT-78 or CUMYL-CYBINACA) is a potent synthetic cannabinoid (indazole-3-carboxamide based). CUMYL4CN-BINACA (SGT-78) is a full agonist at both CB1 and CB2 receptors, with 6.3-fold lower potency at CB2 receptors. At CB1 receptors, its binding affinity is in between that of Δ9-tetrahydrocannabinol (THC) and the prototypic aminoalkylindole cannabinoid WIN55,212-2.
CUMYL-4CN-BINACA (SGT-78) has formal name: 1-(4-Cyanobutyl)-N-(2-phenylpropan-2-yl)-1H-indazole-3-carboxamide. The chemical formula for CUMYL-4CN-BINACA is C22H24N4O with a molecular weight of 360.45
The most likely route of administration for CUMYL-4CN-BINACA (SGT-78) is inhalation via smoking the chemical after it has been sprayed on plant material or vaping it after formulation in liquid. Dosage required for pharmacological effects in humans is unknown.
The toxicity and long-term health effects of recreational CUMYL-4CN-BINACA (SGT-78) use do not seem to have been studied in any scientific context and the exact toxic dosage is unknown.
CUMYL-4CN-BINACA (SGT-78, CUMYL-CYBINACA) is intended for research and forensic purposes in a controlled laboratory for study only and is NOT intended for human consumption.
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