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5F-AB-PINACA also known as 5-Fluoro-AB-PINACA is an indazole-based synthetic cannabinoid that is derived from a series of compounds originally developed by Pfizer in 2009 as an analgesic medication. 5F-AB-PINACA has been reported to be a potent agonist of the CB1 receptor and CB2 receptor with EC50 values of 0.48 nM and 2.6 nM respectively.
5F-AB-PINACA has formal name: N-[(2S)-1-amino-3-methyl-1-oxobutan-2-yl]-1-(5-fluoropentyl)indazole-3-carboxamide is a white powder. The chemical formula is C18H25FN4O2 with a molecular weight of 348.422 g/mol and a 99% purity with a melting point of 85.3 °C.
Since 5F-AB-PINACA is the fluorinated derivative of AB-PINACA, and the latter is being used as a synthetic cannabinoid in so-called ‘Spice’ mixtures, intended to mimic the psychoactive effects of cannabis, it seems plausible that 5F-AB-PINACA is also used as a legal alternative to herbal cannabis.
We have not data concerning the toxicity, reproductive impact and carcinogenic/mutagenic potential of 5F-AB-PINACA.
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5F-AB-PINACA is intended for research and forensic purposes in a controlled laboratory for study only and is NOT intended for human consumption.
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