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4-CMC (also known as 4-Chloromethcathinone and Clephedrone) is potent synthetic analog of methcathinone. Also 4-CMC is a cathinone similar to MDMA, is a substrate at the DAT, SERT and NET with potent, DAT/SERT releasing capabilities and 4-CMC substitutes for cocaine, methamphetamine, and MDMA. 4-CMC used activator of ryanodine receptors while being an inhibitor of SERCA CA2+ pumps which increases the cytosolic free calcium concentration.
4-CMC has formal name: 1-(4-chlorophenyl)-2-(methylamino)-1-propanone. The chemical formula for 4-CMC is C10H12ClNO with a molecular weight of 197.66
Effects of 4-CMC depends on the route of administration such that oral ingestion results in a euphoric effect, while snorting results in a speed-like effect accompanied by agitation, increased concentration, and increased self-confidence.
The toxicity and long-term health effects of recreational 4-CMC use do not seem to have been studied in any scientific context and the exact toxic dosage is unknown.
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4-CMC is intended for research and forensic purposes in a controlled laboratory for study only and is NOT intended for human consumption.
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